Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS.
Identifieur interne : 000046 ( Main/Exploration ); précédent : 000045; suivant : 000047Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS.
Auteurs : Yannan Zhao [République populaire de Chine] ; Hong Yu [République populaire de Chine] ; Jian-Min Zhou [République populaire de Chine] ; Steven M. Smith [Australie] ; Jiayang Li [République populaire de Chine]Source :
- Trends in plant science [ 1878-4372 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Chloroplastes, Espèces réactives de l'oxygène, Malates, Mitochondries.
- Arabidopsis, Oxydoréduction.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Malates, Reactive Oxygen Species.
- metabolism : Chloroplasts, Mitochondria.
- Arabidopsis, Oxidation-Reduction.
Abstract
In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to programmed cell death (PCD). We propose the term 'malate circulation' to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell.
DOI: 10.1016/j.tplants.2020.01.010
PubMed: 32304657
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Smith</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia. Electronic address: steven.smith@utas.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; School of Natural Sciences, University of Tasmania, Hobart, TAS 7001</wicri:regionArea><wicri:noRegion>TAS 7001</wicri:noRegion></affiliation></author><author><name sortKey="Li, Jiayang" sort="Li, Jiayang" uniqKey="Li J" first="Jiayang" last="Li">Jiayang Li</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: jyli@genetics.ac.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Trends in plant science</title><idno type="eISSN">1878-4372</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arabidopsis (MeSH)</term><term>Chloroplasts (metabolism)</term><term>Malates (metabolism)</term><term>Mitochondria (metabolism)</term><term>Oxidation-Reduction (MeSH)</term><term>Reactive Oxygen Species (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Arabidopsis (MeSH)</term><term>Chloroplastes (métabolisme)</term><term>Espèces réactives de l'oxygène (métabolisme)</term><term>Malates (métabolisme)</term><term>Mitochondries (métabolisme)</term><term>Oxydoréduction (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Malates</term><term>Reactive Oxygen Species</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Chloroplasts</term><term>Mitochondria</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Chloroplastes</term><term>Espèces réactives de l'oxygène</term><term>Malates</term><term>Mitochondries</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Arabidopsis</term><term>Oxidation-Reduction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Arabidopsis</term><term>Oxydoréduction</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to programmed cell death (PCD). We propose the term 'malate circulation' to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Automated" Owner="NLM"><PMID Version="1">32304657</PMID><DateCompleted><Year>2020</Year><Month>11</Month><Day>09</Day></DateCompleted><DateRevised><Year>2020</Year><Month>11</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1878-4372</ISSN><JournalIssue CitedMedium="Internet"><Volume>25</Volume><Issue>5</Issue><PubDate><Year>2020</Year><Month>05</Month></PubDate></JournalIssue><Title>Trends in plant science</Title><ISOAbbreviation>Trends Plant Sci</ISOAbbreviation></Journal><ArticleTitle>Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS.</ArticleTitle><Pagination><MedlinePgn>446-454</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1360-1385(20)30027-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.tplants.2020.01.010</ELocationID><Abstract><AbstractText>In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to programmed cell death (PCD). We propose the term 'malate circulation' to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell.</AbstractText><CopyrightInformation>Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Yannan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Hong</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Jian-Min</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Steven M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia. Electronic address: steven.smith@utas.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Jiayang</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Plant Genomics, and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: jyli@genetics.ac.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Trends Plant Sci</MedlineTA><NlmUniqueID>9890299</NlmUniqueID><ISSNLinking>1360-1385</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008293">Malates</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017382">Reactive Oxygen Species</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D017360" MajorTopicYN="Y">Arabidopsis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002736" MajorTopicYN="N">Chloroplasts</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008293" MajorTopicYN="Y">Malates</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008928" MajorTopicYN="N">Mitochondria</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010084" MajorTopicYN="N">Oxidation-Reduction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017382" MajorTopicYN="N">Reactive Oxygen Species</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">chloroplast-to-mitochondrion communication</Keyword><Keyword MajorTopicYN="Y">malate circulation</Keyword><Keyword MajorTopicYN="Y">malate valve</Keyword><Keyword MajorTopicYN="Y">programmed cell death</Keyword><Keyword MajorTopicYN="Y">reactive oxygen species</Keyword><Keyword MajorTopicYN="Y">reducing power</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>09</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>12</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>01</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>11</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32304657</ArticleId><ArticleId IdType="pii">S1360-1385(20)30027-3</ArticleId><ArticleId IdType="doi">10.1016/j.tplants.2020.01.010</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Zhao, Yannan" sort="Zhao, Yannan" uniqKey="Zhao Y" first="Yannan" last="Zhao">Yannan Zhao</name></noRegion><name sortKey="Li, Jiayang" sort="Li, Jiayang" uniqKey="Li J" first="Jiayang" last="Li">Jiayang Li</name><name sortKey="Yu, Hong" sort="Yu, Hong" uniqKey="Yu H" first="Hong" last="Yu">Hong Yu</name><name sortKey="Zhou, Jian Min" sort="Zhou, Jian Min" uniqKey="Zhou J" first="Jian-Min" last="Zhou">Jian-Min Zhou</name></country><country name="Australie"><noRegion><name sortKey="Smith, Steven M" sort="Smith, Steven M" uniqKey="Smith S" first="Steven M" last="Smith">Steven M. 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